Bill of Materials (BOMs) have been present in the shipping of physical products for decades, but as more modern systems (including AI) have come to rely increasingly on software and data, these elements are now essential to capture as well. Software Bill of Materials (SBOMs) are gaining adoption in industry due to increasing software complexity, emerging regulatory requirements (e.g., FDA, CRA), and the expansion of software’s role in critical systems (automotive, medical, space, industrial, etc.). The sheer scale of SBOM metadata generated, the diverse information needed across the software lifecycle, and the need to leverage this data for various risk analyses (security, license, operational, safety, AI) require robust solutions and different perspectives on this material. This keynote will look at the current challenges in the SBOM landscape in terms of generating and maintaining such data. It will explore the challenges that are there for being able to extract knowledge from the BOM metadata for continuous safety compliance for products that may be leveraging open source components in safety critical domains.